Custom Cats: How Genetic Engineering is Changing the World of Pets

Grant Carroll asked:




When people hear the phrase “genetically modified organism” (GMO), They picture fruits, veggies or grain that’s been altered in some way to be cheaper or produced more abundantly. Plant GMOs are usually made with the purpose of solving hunger problems around the world by producing enough food to feed humanity’s exploding population. However, now the term GMO can be applied to something many of us hold dear in our lives…our pets. The company Allerca Pet Lifestyles from California announced last month that they will be selling kittens next year that have been genetically modified to be hypoallergenic. Humans have altered animal genomes for thousands of years through artificial selection (breeding), and even though this new form of genetic tinkering needs to be thoroughly tested before it’s put up for sale, demand is bringing it rushing into the market.

It is hard for one to argue completely against humans altering other animals’ genomes, especially since we’ve already been doing it for much of our history. Diverse breeds of dogs and cats have arisen over the millennia through human efforts of artificial selection. Natural selection created the wild wolves and dogs from which our domesticated friends descended. One could argue that since we’ve already changed animal DNA to fit our desires and needs, there is nothing unethical about genetically modifying today’s pets. It just accomplishes in one generation what usually takes several generations of breeding. It also creates phenotypes that we might never see arise naturally.

One thing that many people agree on is the need for extensive testing before this technology goes to market. The PETA has argued that there is no way of knowing the long-term effects of genetic engineering on a cat’s genome, and they’re right. To date, no such study has been done proving that genetic engineering is completely safe for any animal. In this particular case, scientists have silenced a gene is cats that produces their most common allergen. The gene still exists, but it’s not able to produce it’s protein.
What needs to be done is extensive research over many years to study not only the genetically modified individuals but also their offspring.

In spite of this, there seems to be nothing that can slow the tide of selling GMO pets. Proposed bills that would ban their sale failed in California last year. Though many people protest, GMO pets are coming to market. Hopefully there won’t be too much damage done.

DIY Genetics
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Aging Seen Without The Emperor’S New Clothes

Dov Henis asked:




Aging Seen Without The Emperor’s New Clothes



A. Aging, lifetime and age

Aging = to become old, show the effects or the characteristics of increasing age, the increasing liferime. The effects and characteristics of not only the totality of the system, but also of each and every component, and of components of the components of the system. The system is the totality of the components.

lifetime = the duration of the existence of a living being, an organism, or an inanimate thing, a material, star or subatomic particle.

age = the length of an existence extending from its beginning to any given time.

B. More and more research works related to old age are published in scientific periodicals

The lengthening list of work-accounts comprises a wide array of subjects apparently related to old age, including:

- A variety of constitutional impairments,

- a variety of impaired biological processes,

- a variety of impaired genetic materials and expressions,

- a great variety of suggested things to consume or do or avoid for alleviating the symptoms,

- and a great variety of anti-aging suggestions.

C. Some examples of statements:

- A little stress may keep cells youthful.

- Intestinal stem cells, that replenish the lining, go awry in elderly flies, similar to what happens in certain human stem cell populations.

- Yeast, worms and people may age by similar mechanisms.

- Nearly all organisms experience aging.

- In aging muscles and neurological problems, energy greedy organs, there are mitochondria

dysfunctions.

- Age-related growing ‘leakiness’ in cell nucleus membrane may contribute to aging and even to diseases such as Parkinson’s and Alzheimer’s.

- Age-Related Hearing Impairment, presbycusis, is a complex elderlies disease caused by

overexpression of glutamate due to interaction between environmental and genetic factors.

D. Right they are: “Nearly all organisms experience aging”. But why “nearly”?

Why don’t “scientists” accept the obvious fact that genes are organisms and “experience aging”, too?

Not only yeast, worms and people. Also genes and the interdependent-genes-communes, genomes. Theye are both organisms. They are alive. It is their “lifehood” that makes us and all life forms “alive”.

By plain common sense – my favorite scientific approach – they should also be “experiencing aging”…

E. The aging of genes contributes to organisms aging

Since a genome is a cooperative commune of interdependent genes, many of its member genes “modulate its aging” to various extents at various time-rates depending on circumstances and environment and on their individual composition and functioning history. Various things happen to them or affect them and impair their functionalities.

In my plain commonsensical mind “interaction between environmental and genetic factors” is a description of organism’s “aging”. And in my boy’s-like view of the emperor’s new clothes organism’s aging comprises aging of its genes-genome, and genes and genomes age as we age, and we age also as a result of the aging of our genes and genomes…

F. Finally, re “Theories about human cellular aging supported by new research”

http://www.eurekalert.org/pub_releases/2008-12/asfc-bta111908.php

“Research presented at American Society for Cell Biology conference:

Aging yeast cells accumulate damage over time, but they do so by following a pattern laid down earlier in their life by diet as well as the genes that control metabolism and the dynamics of cell structures such as mitochondria, the power plants of cells.”

Cellular Aging? What is Cellular Aging?

Complexly instrumented future spacestations accumulate damage over time, and their residents, too, age and accumulate damage over time. Yes, the functionality of the stations’ residents and of their intruments and equipment is impaired with age. Wonder why?

The reason for the impairment with age of the highly active instrumented-equipped stations and of their resident crew is that they “follow a pattern laid down earlier in their life by diet as well as by the residents who control metabolism and the dynamics of the stations’ structures such as mitochondria, their power plants.”

G. Enough. Cells just house organisms. The resident genes-genomes are THE organisms.



About time that “scientists” refresh conceptions and comprehensions and attitudes and research plannings and peer-reviewings. Let their science evolve…

Dov Henis

(Comments From The 22nd Century)

http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q–?cq=1

EVOLUTION Beyond Darwin 200

http://www.physforum.com/index.php?showtopic=14988&st=405&#entry396201

http://www.the-scientist.com/community/posts/list/100/122.page#1407



Genetic Biotechnology
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Open Source Food and Genetic Engineering – Michael Pollan

ForaTv asked:


Complete video at: fora.tv “The real key to genetic engineering is control of intellectual property of the food crops that we depend on,” says author Michael Pollan of companies like Monsanto. He advocates an open source GE model. —– Farming has become an occupation and cultural force of the past. Michael Pollan’s talk promoted the premise — and hope — that farming can become an occupation and force of the future. In the past century American farmers were given the assignment to produce …

Somatic Gene Therapy

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Recombinant DNA

scatterbrain73 asked:


A 3D animation illustrating the process by which a protein is mass-produced using spliced DNA and bacterial replication.

Genetic Engineering Center

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